Ciliary and Flagellar Dynamics
PublicA study of the factors that regulate ciliary beating was conducted in an effort to better understand the dynamics of cilia and flagella. A model titled the Geometric Clutch Hypothesis (GCH) was first analyzed and then extended. The model used a constant force for the force exerted by dynein. After analyzing the original GCH, the model was then extended to incorporate the effects of a time-dependent varying dynein force as well as the effects of calcium (Ca2+). After proposing and implementing two ordinary differential equations for a varying dynein force, the results were analyzed and are presented in this report. Notable findings included simulations that produced life-like ciliary beating and simulations that were consistent with experimental data regarding the effects of Ca2+.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- E-project-042213-162628
- Advisor
- Year
- 2013
- Date created
- 2013-04-22
- Resource type
- Major
- Rights statement
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- In Collection:
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CiliaryAndFlagellarDynamics.pdf | Public | Download |
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