The goal of this MQP was to identify and characterize differentially expressed genes associated with Listeria monocytogenes infection in two strains of mice, BALB/cbyj (Listeria sensitive) and C57BL/6ByJ (Listeria resistant). We identified several genes both upregulated and deregulated by the host during infection, and mapped one gene's chromosomal location (though inconclusively) to gain a more complete understanding of the biochemical processes involved in the innate immune response.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Tromp, Katherine M.
• Casey, Ryan Edward

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-122104-220151

Advisor

• Adams, David S.

Year

• 2004

Date created

• 2004-12-21

Resource type

• Major Qualifying Project

Major

• Biochemistry

Rights statement

• In Copyright