MEX-3 is an RNA-binding protein (RBP) about which very little is known. This study aims to uncover more information about the function of MEX-3, as well as its interactions with other RBPs. The study used RNAi to knock down certain RBPs in C. elegans and examine the effect on the expression pattern of MEX-3. Results indicated that GLD-3, PUF-3, LARP-5, and MEX-5 play a role in MEX-3 repression, and that LARP-1 plays a role in promoting MEX-3 expression.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Prescott, Rachel Ann

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042716-223003

Advisor

• Heilman, Destin

Year

• 2016

Sponsor

• University of Massachusetts Medical School

Date created

• 2016-04-27

Resource type

• Major Qualifying Project

Major

• Biochemistry

Rights statement

• In Copyright