Recent research suggests that the absence of the chemokine SDF1- plays a role in the initiation and progression of cancer. Our lab attempted to produce large quantities of SDF1- for testing, analysis, and evaluation of its properties as a possible cancer therapeutic. SDF1- was successfully expressed and partially purified. It was also tested for chemotaxis of various cancer cells. It was found that SDF1- does not induce chemotaxis in all cancer cell lines.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Jarbadan, Nancy Ruth
• Bruce-Morales, Michelle Anasta
• Wischhof, Erik Matthew

Publisher

• Worcester Polytechnic Institute

Identifier

• 00D132M

Advisor

• Adams, David S.

Year

• 2000

Date created

• 2000-01-01

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright