There exists a need for inexpensive and efficient methods to isolate single cells, especially single tumor cells for single cell analysis to improve treatment methods. We developed a microfluidic device that traps single beads ranging from 38 to 45 µm, similar to mammalian cells. Our results suggest our device could trap single beads in 60 µm microwells, indicating this device could allow isolation of similarly-sized cells. Our device could be used for pharmacological testing for personalized medicine and other applications.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Tierney, Emily Rose
• Krupp, Kelsey Elizabeth
• Hemond, Meghan Ashley

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-043015-120244

Advisor

• Ambady, Sakthikumar
• Albrecht, Dirk

Year

• 2015

Date created

• 2015-04-30

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Rights statement

• In Copyright

Last modified

• 2020-11-19