Student Work
Automated System for High-throughput Chemical Screening in C. elegans
PublicDownloadable Content
open in viewerHigh-throughput screening of C. elegans can be used to identify drugs for treatment of neuropsychiatric disorders. These experiments are currently conducted manually, which is time-consuming and hands-on. We designed an automated chemical delivery system, using open-source electronics and rapid prototyped hardware, costing <$300. Our system sequentially delivers chemicals from a 96-well microplate, with low cross-contamination (<0.01%) and satisfactory switching speed (<1 min) between chemicals. We validated our system by reproducing dose-response results published in previous C. elegans literature.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- E-project-043015-132319
- Advisor
- Year
- 2015
- Date created
- 2015-04-30
- Resource type
- Major
- Rights statement
Relations
- In Collection:
Items
Items
Thumbnail | Title | Visibility | Embargo Release Date | Actions |
---|---|---|---|---|
Automated_Chemical_Screening.pdf | Public | Download |
Permanent link to this page: https://digital.wpi.edu/show/0g354h186