Past experimental data has suggested that some unknown growth factor expressed by adult but not young rat hepatocytes is responsible for arresting proliferation. To begin to identify this growth factor, this project utilizes a method recently pioneered by Clontech Laboratories called Suppression Subtractive Hybridization (SSH) to compare RNA sequences found in young and adult rat hepatocytes. Future projects will use the acquired data to eventually clone and identify the functional growth factor.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Convery, Erin Patricia

Publisher

• Worcester Polytechnic Institute

Identifier

• 01D283M

Advisor

• Rulfs, Jill

Year

• 2001

Date created

• 2001-01-01

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright