Assessment of neuromuscular blockade during anesthetization is achieved using the Train of Four (TOF) monitoring technique. However, current devices are limited to conditions in which the hand can move freely. The goal of this project was to design, prototype, and test a device which extends the TOF technique to conditions where movement is restricted. Interviews and surveys were conducted with stakeholders and university students to get feedback on preliminary designs. The resulting device consists of a thumb-mounted balloon, which converts the force due to thumb twitches into pressure, which then acts as the physical analog to muscle response. This pressure is transduced and analyzed to produce a TOF count and TOF ratio. A prototype was constructed and tested on human subjects.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Dillon, Kyler Bailey
• Crofts, Edward Gabriel
• Beauregard, Christopher Robert
• McNamara, Kinsey
• Bergstrom, Nicholas R.

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042519-103715

Advisor

• Lee, Kwonmoo
• Skorinko, Jeanine LM
• Sabuncu, Ahmet Can

Year

• 2019

Date created

• 2019-04-25

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering
• Mechanical Engineering

Rights statement

• In Copyright

License

• All rights reserved