Student Work
Defining the role of a conserved G protein activator RIC-8 in neuronal heat shock response
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open in viewerStress response, which is a complex interconnection of various pathways and proteins, has the capacity to protect an organism from cellular stress. Previous research in the Nechipurenko lab has shown that a non-canonical Gα protein guanine nucleotide exchange factor RIC-8 localizes to the primary cilium, and when heat shocked, the cilia of ric-8 mutant C. elegans are shorter than wild-type cilia. These preliminary findings suggest that RIC-8 contributes to protecting cilia against heat stress. The aims of this project were to determine whether RIC-8 is required for stress-dependent cilia remodeling and to identify additional genes involved in this process.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- 105691
- E-project-042723-002447
- Palabra Clave
- Advisor
- Year
- 2023
- Date created
- 2023-04-27
- Resource type
- Major
- Source
- E-project-042723-002447
- Rights statement
- Última modificación
- 2023-06-18
Las relaciones
- En Collection:
Elementos
Elementos
Miniatura | Título | Visibilidad | Embargo Release Date | Acciones |
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LaBombard_MQP_final_paper_submission_PDF_1.pdf | Público | Descargar |
Permanent link to this page: https://digital.wpi.edu/show/7h149t195