Student Work

 

Improving Large Scale Culture for Anchorage Dependent Cells Public

Downloadable Content

open in viewer

Chronic diseases are a prevalent and expensive health conditions in the US, with 133 million people suffering from a chronic disease. Tissue engineering, particularly mesenchymal stem cell(MSC) approaches, show great potential in meeting the need for treatments. There is a need for an improved scaffold to promote proliferation of adherent cells within bioreactors. This project aims to solve this gap in technology by constructing a 3-D scaffold of a novel material that would solve production issues of MSC’s. A literature review found materials that were nontoxic, flexible, and allowed cellular adhesion. Experiments quantified cell seeding and proliferation on varying materials to select a material for final design. A multilayer scaffold of stainless steel mesh was selected for final design.

Creator
Publisher
Identifier
  • E-project-051320-130755
Advisor
Year
  • 2020
Date created
  • 2020-05-13
Resource type
Major
Rights statement
License

Relationships

In Collection:

Items

Permanent link to this page: https://digital.wpi.edu/show/5712m9086