. . . "Worcester Polytechnic Institute" . . "2020" . "http://rightsstatements.org/vocab/InC/1.0/" . "This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review." . . "Rao, Pratap M." . "Page, Raymond L." . "StudentWork" . "2020-08-21T21:16:25.308354913-04:00"^^ . "E-project-051320-130755" . "depositor@wpi.edu" . . "Coutts, Colin William" . "Donovan, Emily" . "Suchanek, Kyle Stephen" . "Nikulina, Maria" . "2020-05-13" . . "Major Qualifying Project" . "Improving Large Scale Culture for Anchorage Dependent Cells" . "Biomedical Engineering" . . "Chronic diseases are a prevalent and expensive health conditions in the US, with 133 million people suffering from a chronic disease. Tissue engineering, particularly mesenchymal stem cell(MSC) approaches, show great potential in meeting the need for treatments. There is a need for an improved scaffold to promote proliferation of adherent cells within bioreactors. This project aims to solve this gap in technology by constructing a 3-D scaffold of a novel material that would solve production issues of MSC’s. A literature review found materials that were nontoxic, flexible, and allowed cellular adhesion. Experiments quantified cell seeding and proliferation on varying materials to select a material for final design. A multilayer scaffold of stainless steel mesh was selected for final design." . . "ActiveFedora::Aggregation::ListSource" . . . . .