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Effects of PTEN Loss and Activated KRAS Overexpression on Viscoelasticity, Adhesion, and Mechanosensitivity of Breast Epithelial Cells
Keyword:
Cellular Mechanics
,
Atomic Force Microscopy
,
Breast Cancer
,
Cancer Dormancy
,
Triple Negative
, and
Adhesion
Creator:
Linthicum, Will H
Advisor:
Wen, Qi
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-08-08
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Multi-Layered Oxygen Tension Maps of the Retina
Keyword:
Diabetes
,
Retina
,
Imaging
, and
Phosphorescence
Creator:
Norige, Adam Stuart
Advisor:
Shonat, Ross D.
Publisher:
Worcester Polytechnic Institute
Date Created:
2004-04-30
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Applications of Deep Learning in Brain Injury Biomechanics and Spine Image Registration
Keyword:
Spine Image Registration
,
Image-guided Surgery
,
Concussion
,
Deep Learning
, and
Brain Injury
Creator:
Wu, Shaoju
Advisor:
Ji, Songbai
Publisher:
Worcester Polytechnic Institute
Date Created:
2022-08-03
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
In vivo monitoring of collagen-sponge remodeling using MRI
Keyword:
collage remodelling
,
MRI
, and
in vivo
Creator:
Kandasamy, Sivakumar P
Advisor:
Sotak, Christopher H.
Publisher:
Worcester Polytechnic Institute
Date Created:
2007-03-26
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Evaluation of the Effects of Hyperbaric Dive Environments on the Autonomic Nervous System Using Principal Dynamic Mode Analysis
Keyword:
principal dynamic mode
,
decompression sickness
,
SCUBA dive
,
heart rate variability
,
hyperbaria
, and
autonomic nervous system
Creator:
Bai, Yan
Advisor:
Chon, Ki H.
Publisher:
Worcester Polytechnic Institute
Date Created:
2011-08-11
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Reconfigurable Fiducial-Integrated Modular Needle Driver For MRI-Guided Percutaneous Interventions
Keyword:
Registration
,
medical robot
,
image-guided surgery
,
needle steering
, and
MRI
Creator:
Ji, Wenzhi
Advisor:
Fischer, Gregory S.
Publisher:
Worcester Polytechnic Institute
Date Created:
2013-04-25
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Engineering silk fibroin scaffolds to model hypoxia in neuroblastoma
Keyword:
Hypoxia
,
Silk Fibroin
,
Neuroblastoma
, and
Scaffold
Creator:
Ornell, Kimberly J
Advisor:
Coburn, Jeannine M
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-08-07
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Designing Biomaterial Surfaces to Enhance Adhesion at the Skin-Implant Interface
Keyword:
keratinocytes
,
neuroprosthetics
,
percutaneous seal
,
Cell adhesion
, and
percutaneous implant
Creator:
Ting, Cara M
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2011-05-03
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Development of an Automated Anesthesia System for the Stabilization of Physiological Parameters in Rodents
Keyword:
Anesthesia
,
LabVIEW
, and
Fuzzy Logic Control
Creator:
Hawkins, Kevin Michael
Advisor:
Shonat, Ross D.
Publisher:
Worcester Polytechnic Institute
Date Created:
2003-04-24
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Regional Mechanical Function Changes Remain after Ventricular Pacing Cessation: Evidence of Mechanical Cardiac Memory
Keyword:
Cardiac Memory
,
Mechanical function
, and
HDM
Creator:
Skorinko, Jeremy Kenneth
Advisor:
Gaudette, Glenn R.
Publisher:
Worcester Polytechnic Institute
Date Created:
2010-03-27
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Micropatterned Fibrin Hydrogels for Increased Cardiomyocyte Alignment
Keyword:
Electrical stimulation
,
hiPS-CM
,
Micropatterning
,
Cardiac tissue engineering
,
Fibrin scaffold
, and
Cardiac patches
Creator:
English, Elizabeth J
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-12-09
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Development of automated analysis methods for identifying behavioral and neural plasticity in sleep and learning in C. elegans
Keyword:
Associative Learning
,
C. elegans
,
Neural Plasticity
,
Neural Imaging
,
Microfluidics
, and
Sleep
Creator:
Lawler, Daniel E
Advisor:
Albrecht, Dirk
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-12-10
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Characterization and Compensation of Hysteretic Cardiac Respiratory Motion in Myocardial Perfusion Studies Through MRI Investigations
Keyword:
Emission tomography
,
Cardiac Imaging
,
Respiratory Motion
,
Modeling Hysteresis
, and
MRI
Creator:
Dasari, Paul Krupaker Reddy
Advisor:
King, Michael A
and
Mendelson, Yitzhak
Publisher:
Worcester Polytechnic Institute
Date Created:
2014-04-24
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Spatiotemporal Organization of Atrial Fibrillation Using Cross-Bicoherence with Surrogate Data
Keyword:
cross-bicoherence
,
atrial fibrillation
,
cross-bispectrum
,
high order spectral analysis
,
cardiac electrophysiology
, and
surrogate data
Creator:
Jaimes, Rafael
Advisor:
Chon, Ki H.
Publisher:
Worcester Polytechnic Institute
Date Created:
2011-05-19
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Creating a Functional Cardiac Patch From Decellularized Spinach Leaves
Keyword:
iPS-CM
,
decellularized plant
,
tissue engineering
, and
cardiac tissue patch
Creator:
Robbins, Emily
Advisor:
Gaudette, Glenn R.
Publisher:
Worcester Polytechnic Institute
Date Created:
2021-08-06
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Simultaneous Measurement of Oxygen and Carbon Monoxide Saturation using Pulse Oximeters
Keyword:
Pulse Oximeters
and
oxygen and carbon monoxide saturation
Creator:
Vasudevan, Shanthi
Advisor:
Mendelson, Yitzhak
Publisher:
Worcester Polytechnic Institute
Date Created:
2011-04-26
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Tuning the Biophysical and Biochemical Cues of Fibrin Microthread Scaffolds Towards the Treatment of Volumetric Muscle Loss
Keyword:
tissue engineering
,
fibrin
,
skeletal muscle regeneration
,
biomaterials
,
volumetric muscle loss
, and
microthreads
Creator:
Carnes, Meagan E.
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2020-09-29
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
RVD2: An ultra-sensitive variant detection model for low-depth heterogeneous next-generation sequencing data
Keyword:
variant detection; Bayesian statistics; graphical
Creator:
He, Yuting
Advisor:
Flaherty, Patrick J.
Publisher:
Worcester Polytechnic Institute
Date Created:
2014-04-29
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Designing Modular Fibrin Composite Scaffolds for Enhanced Ventricular Myocardium Regeneration
Keyword:
cardiac patch
and
fibrin composite
Creator:
Chrobak, Megan O'Brien
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2017-12-04
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Comparison of Alternative Rigid Sternal Fixation Techniques
Keyword:
Osteoporosis
,
malunion
,
Sternum
, and
Rigid Fixation
Creator:
Dieselman, John Conrad
Advisor:
Billiar, Kristen
Publisher:
Worcester Polytechnic Institute
Date Created:
2012-01-12
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Fibrin Microthreads Promote Stem Cell Growth for Localized Delivery in Regenerative Therapy
Keyword:
infarct
,
myocardium
,
microthreads
,
human mesenchymal stem cells
, and
Fibrin
Creator:
Murphy, Megan K
Advisor:
Pins, George D
,
Gaudette, Glenn R.
, and
Rolle, Marsha Whitney
Publisher:
Worcester Polytechnic Institute
Date Created:
2008-09-02
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Detection of Spatial and Temporal Interactions in Renal Autoregulation Dynamics
Keyword:
synchronization
,
laser speckle imaging
,
renal autoregulation
, and
time-varying
Creator:
Scully, Christopher
Advisor:
Chon, Ki H.
Publisher:
Worcester Polytechnic Institute
Date Created:
2013-06-24
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
An Affordable Portable Obstetric Ultrasound Simulator for Synchronous and Asynchronous Scan Training
Keyword:
Ultrasound
,
Simulation
,
Education
, and
Obstetric
Creator:
Liu, Li
Advisor:
Pedersen, Peder C.
Publisher:
Worcester Polytechnic Institute
Date Created:
2016-01-13
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
A Computer-Based Cascaded Modeling and Experimental Approach to the Physical Characterization of a Clinical Full-Field Mammography System
Keyword:
screen-film
,
mammography
, and
linear cascade model
Creator:
Ved, Hetal R
Advisor:
Karellas, Andrew
Publisher:
Worcester Polytechnic Institute
Date Created:
2002-09-20
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Modeling the Dynamic Composition of Engineered Cartilage
Keyword:
biosynthesis
,
Tissue Engineering
, and
chondrocyte
Creator:
Wilson, Christopher G
Advisor:
Kohles, Sean S.
and
Bonassar, Lawrence J.
Publisher:
Worcester Polytechnic Institute
Date Created:
2002-03-26
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Changes in Passive and Dynamic Mechanical Environments Promote Differentiation to a Contractile Phenotype in Vascular Smooth Muscle Cells
Keyword:
smooth muscle cell
,
3D culture
,
cell-derived matrix
,
Vascular Tissue Engineering
, and
phenotype
Creator:
Reidinger, Amanda Zoe
Advisor:
Rolle, Marsha Whitney
Publisher:
Worcester Polytechnic Institute
Date Created:
2015-04-29
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Design and Performance of a Localized Fiber Optic, Near-Infrared Spectroscopic Prototype Device for the Detection of the Metabolic Status of “Vulnerable Plaque”: in-vitro Investigation of Human Carotid Plaque
Keyword:
tissue lactate
,
vulnerable plaque
,
atherosclerosis
,
optical spectroscopy
, and
tissue pH
Creator:
Khan, Tania Nur
Advisor:
Peura, Robert A.
,
Soller, Babs R.
, and
Tuft, Richard
Publisher:
Worcester Polytechnic Institute
Date Created:
2003-01-08
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Machine Learning Pipelines for Deconvolution of Cellular and Subcellular Heterogeneity from Cell Imaging
Keyword:
Cell Migration
,
Hologram Imaging
,
Machine Learning (Deep Learning)
,
Time Series Analysis
, and
Cell Heterogeneity
Creator:
Wang, Chuangqi
Advisor:
Lee, Kwonmoo
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-08-12
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Portable Bioimpedance System for Early Detection and Prevention of Pressure Injuries
Keyword:
Ulcer
,
Sensor
,
Pressure
,
Bioimpedance
,
Detection
, and
Injury
Creator:
Harvey, Joshua R
Advisor:
Mendelson, Yitzhak
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-09-18
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
An Image-Based Method to Measure Joint Deformity in Inflammatory Arthritis
Keyword:
HRpQCT
,
method
,
non-linear surface transformation
,
CT
,
Imaging
,
inflammatory arthritis
,
MCP
, and
coherent point drift
Creator:
Henchie, Travis F
Advisor:
Troy, Karen
Publisher:
Worcester Polytechnic Institute
Date Created:
2018-04-26
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Centritubing: Using Centrifugal Force to Create Self-Assembled Tubular Tissue Constructs
Keyword:
Tissue Engineering
,
Self-Assembly
,
centrifugal force
,
TEBV
, and
tubular construct
Creator:
Jones, Craig
Advisor:
Rolle, Marsha Whitney
Publisher:
Worcester Polytechnic Institute
Date Created:
2013-01-09
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
The Incorporation of Decellularized Cardiac ECM into Fibrin Microthreads
Keyword:
extracellular matrix
,
decellularized
, and
microthreads
Creator:
Marengo, Kaitlyn A
Advisor:
Gaudette, Glenn R.
Publisher:
Worcester Polytechnic Institute
Date Created:
2017-05-26
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Evaluation of Canine Fracture Fixation Bone Plates
Keyword:
fixation
,
evaluation
,
fracture
,
Mechanical
,
bone
, and
plate
Creator:
Tacvorian, Edward
Advisor:
Gaudette, Glenn R.
Publisher:
Worcester Polytechnic Institute
Date Created:
2012-11-05
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Deep Transfer Learning Applied to Time-series Classification for Predicting Heart Failure Worsening Using Electrocardiography
Keyword:
Heart failure
,
Heart failure worsening prediction
,
Transfer learning
,
Machine Learning
,
Time series analysis
, and
Manifold learning
Creator:
Pan, Xiang
Advisor:
Lee, Kwonmoo
Publisher:
Worcester Polytechnic Institute
Date Created:
2020-04-20
Resource Type:
Dissertation
Degree:
MS
Unit (Department):
Biomedical Engineering
A Comparative Analysis of the Biomechanics and Biochemistry of Cell-Derived and Cell-Remodeled Matrices: Implications for Wound Healing and Regenerative Medicine
Keyword:
strength
,
fibrin gel
,
glycosaminoglycans
,
tissue growth
,
Regenerative medicine
,
wound-healing model
,
tissue formation
,
human
,
proteoglycans
,
biomechanical characterization
,
UTS
,
biochemical characterization
,
fibroblast-populated
,
growth factors
,
cell-derived matrix
,
mechanics
,
Fibroblasts
,
collagen
,
serum-free
,
extensibility
,
total protein content
,
tension
,
chemically-defined medium
,
thickness
,
cell-remodeled matrix
,
tissue regeneration
,
collagen gel
, and
failure strain
Creator:
Ahlfors, Jan-Eric Wilhelm
Advisor:
Billiar, Kristen
Publisher:
Worcester Polytechnic Institute
Date Created:
2004-05-03
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Oscillatory wall strain reduction precedes arterial intimal hyperplasia in a murine model
Keyword:
Ultrasound
,
intimal hyperplasia
,
biomechanics
,
peripheral artery disease
,
medical imaging
, and
coronary artery disease
Creator:
Favreau, John T
Advisor:
Gaudette, Glenn R.
Publisher:
Worcester Polytechnic Institute
Date Created:
2014-04-25
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Direct cell seeding on collagen-coated silicone mandrels to generate cell-derived tissue tubes
Keyword:
blood vessels
and
vascular tissue enigneering
Creator:
Doshi, Kshama J
Advisor:
Rolle, Marsha Whitney
Publisher:
Worcester Polytechnic Institute
Date Created:
2009-08-28
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Optimization of a Technique for Phosphorescence Lifetime Imaging of Oxygen Tension in the Mouse Retina
Keyword:
Retina
,
Imaging
,
Phosphorescence
, and
eye
Creator:
Kight, Amanda C.
Advisor:
Shonat, Ross D.
Publisher:
Worcester Polytechnic Institute
Date Created:
2002-04-30
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Engineering the Keratinocyte Microenvironment: Harnessing Topography to Direct Cellular Function
Keyword:
dermal–epidermal junction
,
keratinocyte function
,
microtopography
, and
tissue engineered skin
Creator:
Clement, Amanda Lynn
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2015-01-12
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Characterization of soft-tissue response to mechanical loading using nuclear magnetic resonance (NMR) and functional magnetic resonance imaging (fMRI) of neuronal activity during sustained cognitive-stimulus paradigms
Keyword:
tendon
,
NMR
,
fMRI
, and
diffusion
Creator:
Wellen, Jeremy W.
Advisor:
Sotak, Christopher H.
Publisher:
Worcester Polytechnic Institute
Date Created:
2003-04-30
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
A Cell Spheroid Model of Calcific Aortic Valve Disease: The Role of Apoptosis and Oxidative Stress
Creator:
Coutts, Colin
Advisor:
Billiar, Kristen
Publisher:
Worcester Polytechnic Institute
Date Created:
2021-05-21
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Osmotic- and Stroke-Induced Blood-Brain Barrier Disruption Detected by Manganese-Enhanced Magnetic Resonance Imaging
Keyword:
blood-brain barrier
,
osmotic shock
,
manganese-enhanced MRI
, and
rat brain
Creator:
Bennett, David G
Advisor:
Sotak, Christopher H.
Publisher:
Worcester Polytechnic Institute
Date Created:
2007-08-17
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Development of Motion Artifact Rejection Algorithms for Ambulatory Heart Rate and Arterial Oxygen Measurement By A Wearable Pulse Oximeter
Keyword:
Kurtosis
,
Motion Artifacts
,
Adaptive Noise Cancellation
, and
Pulse Oximeters
Creator:
Marwah, Kunal
Advisor:
Mendelson, Yitzhak
Publisher:
Worcester Polytechnic Institute
Date Created:
2012-07-06
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
MRI Contrast Agent Studies of Compartmental Differentiation, Dose-dependence, and Tumor Characterization in the Brain
Keyword:
contrast agent
,
glioma
,
signal decay
,
dose dependence
,
manganese
,
brain
,
compartmental differentiation
,
diffusion
,
tumor
, and
Magnetic Resonance Imaging
Creator:
Shazeeb, Mohammed Salman
Advisor:
Gaudette, Glenn R.
and
Sotak, Christopher H.
Publisher:
Worcester Polytechnic Institute
Date Created:
2010-12-12
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Rat Model of Pre-Motor Parkinson's Disease: Behavioral and MRI Characterization.
Keyword:
aversion
,
resting state connectivity
,
MRI
,
Parkinson's disease
,
animal model
, and
cognition
Creator:
Rane, Pallavi S.
Advisor:
Pins, George D
,
King, Jean A.
, and
Sotak, Christopher H.
Publisher:
Worcester Polytechnic Institute
Date Created:
2011-04-14
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Towards the Fabrication of a Fibrin Based Vascular Network
Keyword:
Vascular Engineering
,
Fibrin
, and
Vasculature
Creator:
Santos, Johanna Eleanor
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2018-08-16
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Engineered Vascular Tissue Generated by Cellular Self-Assembly
Keyword:
Self-Assembly
,
cell-derived
, and
vascular graft
Creator:
Gwyther, Tracy A
Advisor:
Rolle, Marsha Whitney
Publisher:
Worcester Polytechnic Institute
Date Created:
2012-01-13
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Delivering Stem Cells to the Heart
Keyword:
microthreads
,
heart attack
,
hMSC
, and
myocardial infarction
Creator:
Fakharzadeh, Michael
Advisor:
Gaudette, Glenn R.
Publisher:
Worcester Polytechnic Institute
Date Created:
2010-05-03
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Neuronal Correlates of Diacritics and an Optimization Algorithm for Brain Mapping and Detecting Brain Function by way of Functional Magnetic Resonance Imaging
Keyword:
fMRI
,
Neuroimaging
,
Optimization
,
Diacritics
, and
Brain Mapping
Creator:
Bourisly, Ali Khaled
Advisor:
Sotak, Christopher H.
Publisher:
Worcester Polytechnic Institute
Date Created:
2011-04-14
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Passive Resonant Coil Based Fast Registration And Tracking System For Real-Time Mri-Guided Minimally Invasive Surgery
Keyword:
Stereotactic surgery
,
MRI guided intervention
,
Image based registration and tracking
,
Passive imaging coil
, and
Minimally invasive surgery
Creator:
Ma, Yunzhao
Advisor:
Fischer, Gregory S.
Publisher:
Worcester Polytechnic Institute
Date Created:
2013-05-30
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
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