Student Work
Poly--glutamic acid toxicity and insulin delivery in liver cells
PublicThe compound poly--glutamic acid (-PGA) has been shown to have potential use as a drug delivery agent. In this study, cytotoxicity tests were performed using -PGA. Our findings show that -PGA exhibits no cytotoxic effects to cell cultures of human hepatoma cells and do not inhibit differentiation in rat skeletal muscle myoblasts. Further studies using an insulin/-PGA complex were inconclusive, but show potential as a time release agent for insulin delivery.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- 00D107M
- Advisor
- Year
- 2000
- Date created
- 2000-01-01
- Resource type
- Major
- Rights statement
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