The nematode Caenorhabditis elegans changes its surface composition during development, such that an L1 surface antigen is turned off at a later larval stages in response to environmental signals. Worms with mutations in gene srf-6 display the L1 antigen at stages L1 through L4 (Constitutive Larval Display or CLD). Osm-3 mutations affect the worm's chemosensation. A mutation in the osm-3 gene was shown to block CLD in srf-6 mutant worms, indicating that osm-3 activity is required for srf-6 to have its effect.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Montez, Katina Marie.

Publisher

• Worcester Polytechnic Institute

Identifier

• 05D524M

Advisor

• Politz, Samuel M.

Year

• 2005

Date created

• 2005-01-01

Resource type

• Major Qualifying Project

Major

• Biochemistry

Rights statement

• In Copyright