Cellular adhesion is an essential factor in development, serving both structural and communicatory functions, defects in which have been implicated in a wide range of diseases, including cardiovascular and neurodegenerative disorders. Kekkon5, a transmembrane protein in Drosophila containing the atypical combination of leucine-rich repeats and immunoglobulin domains, has been implicated in cellular adhesion and related signaling pathways. Deletion studies with Kekkon5 have demonstrated the necessity of both extracellular and intracellular domains for full activity and function.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Kolodzy, Christina Lynn

Contributori

• Ryder, Elizabeth F.

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042108-144532

Advisor

• Duffy, Joseph B.

Year

• 2008

Date created

• 2008-04-21

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright

Ultima modifica

• 2023-11-03