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Design of an Electrical Biopsy Tool for White Light Colonoscopy

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Detection and classification of polyps during regular colonoscopy screenings are crucial in the treatment and prevention of colorectal cancer. However, the current standard white light colonoscopy and biopsy have limitations in detecting and classifying polyps. The objective of this Major Qualifying Project (MQP) is to develop a colonoscopy probe that can identify the polyps at the time of screening by electrical measurements. It has been shown that the electrical impedance of polyps decreases as a function of neoplastic progression. The proposed probe is based on a snare tool that can fit within an instrument channel of a conventional colonoscopy probe with embedded electrodes to enable electrical impedance measurements. The details of the design, prototyping, and experiments with simulated polyps were documented. The results indicate that our device has the ability to identify cancerous and healthy tissue. This tool could help colonoscopy practitioners with polyp classification by measuring the bioelectrical properties of the polyp tissue in situ.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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Identifier
  • 65611
  • E-project-042822-144859
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Year
  • 2022
Date created
  • 2022-04-28
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