Student Work

Myocardial ischemic factors

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Short periods of ischemia have been shown to protect the heart during future, prolonged ischemic episodes. To isolate factors involved in ischemic preconditioning, New Zealand white rabbit hearts were subjected to episodes of ischemia. The rabbit jejunum was used to assay HPLC fractions of heart effluent. Three factors affecting contractile activity were found: Fraction I, a depressive factor identified as adenosine; Fraction 2, a depressive factor thought to be Met-Enkephalin; and Fraction 3, an excitatory factor suspected to be PGE.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
Creator
Publisher
Identifier
  • 02C001M
Advisor
Year
  • 2002
Date created
  • 2002-01-01
Resource type
Major
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