Student Work
Assessment of the Functionality of Nuclear Export Sequences in Porcine Circovirus 1 VP3
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open in viewerPorcine Circovirus Type 1 (PCV1) is a member of the Circoviridae family. The protein encoded by its third open reading frame (PCV1 VP3) displays onco-specific induction of apoptosis; localization signals have been implicated in this onco-specific activity. Site-directed mutagenesis was applied to assess the functionality of export sequences within PCV1 VP3. The cytoplasmic localization observed after the mutations raise many questions as to the functionality of these export sequences and the possible existence of non-classical sequences within PCV1 VP3.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- E-project-042413-140338
- Advisor
- Year
- 2013
- Date created
- 2013-04-24
- Resource type
- Major
- Rights statement
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Miniatura | Título | Acesso | Embargo Release Date | Ações |
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PCV1_VP3__Final_MQP_Report.pdf | Público | Baixar |
Permanent link to this page: https://digital.wpi.edu/show/wm117q504