Artemisinin, an antimalarial treatment derived from Artemisia annua, reacts with ferrous compounds, generating free radicals unless hindered by antioxidants. High iron levels and low antioxidant levels of cancer cells make artemisinin a potentially effective treatment. We utilized MTT assays to assess artemisinin’s effect on MCF7 breast cancer cells. Artemisinin upregulated cell proliferation and appeared to affect the cells’ morphology, which could impact tumor development.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Hazard, Whitney Jeanne
• German, Rebecca Mary
• Maxim, Reed Alex

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042617-202533

Advisor

• Buckholt, Michael Allan
• Rulfs, Jill

Year

• 2017

Date created

• 2017-04-26

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright