The intestinal microbiome is a complex microbial ecosystem that affects the health of the host organism. We used laboratory and computational methods to study interactions between beneficial and pathogenic microbes within the intestine of C. elegans. We observed the movement of pathogenic yeast through the worm and measured transit time. This data determined modifications of an existing agent-based model. Consistent with findings and literature, the model predicts fewer pathogenic yeast colonize the worm intestine in the presence of beneficial microbes.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Norales, Monet M.
• Daly, Daire D.

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-040621-100718
• 17101

Advisor

• Rao, Reeta Prusty
• Ryder, Elizabeth F.

Year

• 2021

Date created

• 2021-04-06

Resource type

• Major Qualifying Project

Major

• Bioinformatics & Computational Biology

Rights statement

• In Copyright