Using synthetic polymers, scaffolds can be created for tissue engineering. The goal of this project was to fabricate and evaluate porous PCL scaffolds for cartilage-tissue engineering. By varying molecular weight and porosity, scaffolds were ultimately designed for cell seeding. Three molecular weights were tested, as well as four different salt/polymer ratios. High molecular-weight scaffolds with a high salt/polymer ratio proved to be the most promising for in vitro growth of chondrocytes.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Reynolds, Emily Pamela
• Gissel, Matthew Thomas
• Burgess, Billy James

Publisher

• Worcester Polytechnic Institute

Identifier

• 01D252M

Advisor

• Wobbe, Kristin K.

Year

• 2001

Date created

• 2001-01-01

Resource type

• Major Qualifying Project

Major

• Biochemistry
• Chemistry

Rights statement

• In Copyright