In primates, complement-coated invading microbes and immune complexes are efficiently removed from circulation by binding complement receptor-1 (CR1) on erythrocytes, a process known as immune-adherence clearance. This project examines the nature and functionality of complement binding to erythrocytes under normal and pathological conditions. The data identifies key factors associated with the complement-CR1 ligation pathway promoting membrane deformability, helping elucidate a greater understanding of this important, unique erythrocyte function.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Khoory, Joseph Anthony

Contributeurs

• Ghiran, Ionita

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042413-184650

Advisor

• Adams, David S.

Year

• 2013

Sponsor

• Beth Israel Hospital

Date created

• 2013-04-24

Emplacement

• Boston

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright

Dernière modification

• 2023-09-20