Student Work
Do ARX-3 and CSN-5 Protein Subunits Interact with MIG-10 to Promote Axon Outgrowth and Neuronal Migration in C. elegans?
PublicDownloadable Content
open in viewerDuring nervous system development, the cytoplasmic signaling protein MIG-10 activates cellular processes in response to guidance cues which ultimately lead to axonal growth and migration. Interactions between MIG-10 and two candidate downstream proteins, CSN-5 and ARX-3, were studied in vivo, using mutant transgenic C. elegans strains, and in vitro, using a co-immunoprecipitation system. Preliminary results indicate interaction in vitro between MIG-10 and both proteins. In vivo experiments are ongoing.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Contributors
- Publisher
- Identifier
- E-project-053112-103844
- Advisor
- Year
- 2012
- Date created
- 2012-05-31
- Resource type
- Major
- Rights statement
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Thumbnail | Title | Visibility | Embargo Release Date | Actions |
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Meagan_E._Sullender_MQP_Report.pdf | Public | Download |
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