Gliding assays have been the standard tools of the past two decades to analyze the properties of molecular motors. Recently, we have shown that they can be used as model systems to study bending of bio-filaments. There are several approaches in the literature to measure filament deformations. One of the most commonly used approaches is Fourier analysis. In this project, we investigate this technique in great detail using computer simulations, and compare it with another novel technique, namely curvature distributions. We also compare our theoretical predictions and simulation results with experimental measurements of filament bending from actin gliding assays.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Wisanpitayakorn, Pattipong

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042513-155356

Advisor

• Tuzel, Erkan

Year

• 2013

Date created

• 2013-04-25

Resource type

• Major Qualifying Project

Major

• Physics

Rights statement

• In Copyright