This Major Qualifying Project (MQP) addresses an important step in the development of a cure for diabetes: the characterization of an animal model used to study the disease. By applying principles of engineering design, we chose an animal model, a diabetes induction method, and some of the most relevant complications for validating this diabetic animal model. We also designed and implemented the tests used to critically analyze the diabetic complications throughout the course of the disease. These developed protocols are currently being used to characterize a Poly I:C-induced rat model to type 1 diabetes.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• League-Pike, Walker Forrest
• Mason, David Lawrence

Publisher

• Worcester Polytechnic Institute

Identifier

• 04D262M

Advisor

• Shonat, Ross D.

Year

• 2004

Date created

• 2004-01-01

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Rights statement

• In Copyright