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Development of Spatial Optical Coherence Tomography Methods to Characterize Thin Biological Samples

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Obtaining thicknesses of micro-scale samples through noninvasive methods is crucial when dealing with fragile or biological samples. Optical Coherence Tomography (OCT) is an imaging technique which uses low coherence interferometry to create a layered stack of cross-sectional images without directly contacting the sample. An OCT setup was developed for our experimentation, was validated for measurement accuracy with samples of known thickness with an error of ±4.73%, and applied to characterize specific biological samples. Our OCT enables the observation of both, surfaces and internal structures of micro-scale samples.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-043015-164626
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  • 2015
Date created
  • 2015-04-30
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Permanent link to this page: https://digital.wpi.edu/show/rf55z9529