Stromal cells originate from a variety of tissues and may have possible therapeutic applications in tissue repair in myocardial infarcts. This project investigated the relationships between human bone marrow-derived stromal cells (BM/ MSC), dermis-derived stromal cells, and cardiac-derived stromal cells by in vitro characterization for surface markers, secretory profiles, differentiation capacity, and DNA methylation patterns. Cell characterization is important for cell therapies and it helps to better understand the functions of these cell types and the mechanism of actions.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Larson, Shane P.

Contributors

• Molnar, Gyongyi

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042208-180127

Advisor

• Adams, David S.

Year

• 2008

Sponsor

• Genzyme Corporation

Date created

• 2008-04-22

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright