Student Work
Gene expression profiling and functional genomics in bone development
PúblicoBone cell development can be studied using various cell lines in vitro. Analysis of a previously conducted microarray experiment showed a class of "neuronal" genes expressed in an early stage on bone development. These genes include ULIP, protease-nexin 1, and RAS p21 protein activator. They were observed to be expressed in successive stages of osteoblast development in C2C12, MC3T3, and MLO-Y4 cell lines using real-time quantitative PCR. The expression of these genes loosely correlated with changes in cell morphology.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- 04D067M
- Advisor
- Year
- 2004
- Date created
- 2004-01-01
- Resource type
- Major
- Rights statement
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