Student Work
To Stress or Not To Stress: Pesticides and Cellular Stress Response
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open in viewerPesticides are ubiquitous in the environment and are found in human tissues. Using fluorescence microscopy, we examined the effects of the pesticides N-phosphonomethyl glycine (glyphosate) and 2,4-Dichlorophenoxyacetic acid (2,4-D) on formation of stress granules (SGs), cytoplasmic aggregates of silenced mRNPs formed under stress conditions. 2,4-D caused dose-dependent formation of SGs from 1 to 4 mM, while glyphosate caused no SG formation. Our work suggests some pesticides may affect cellular stress responses, and that further research is warranted.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- E-project-032017-162729
- Advisor
- Year
- 2017
- Date created
- 2017-03-20
- Resource type
- Major
- Rights statement
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