"id" |"create_date" |"modified_date" |"depositor" |"title" |"date_uploaded" |"date_modified"|"state"|"proxy_depositor"|"on_behalf_of"|"arkivo_checksum"|"owner"|"alternate_title"|"award"|"includes"|"advisor" |"advisor" |"sponsor"|"center"|"year"|"funding"|"institute"|"school"|"major" |"major" |"sdg"|"note" |"alternative_title"|"label"|"relative_path"|"import_url"|"resource_type" |"creator" |"creator" |"creator" |"contributor"|"description" |"abstract"|"keyword"|"license"|"rights_notes"|"rights_statement" |"access_right"|"publisher" |"date_created"|"subject"|"language"|"identifier" |"based_near"|"related_url"|"bibliographic_citation"|"source"|"version" |"permalink" "nc580q656"|"2020-08-22T06:39:24.708+00:00"|"2024-03-12T16:08:05.590+00:00"|"depositor@wpi.edu"|"Investigating the Unusual Gene Structure of DNA Primase in Mycobacteriophage Subclusters"|"2020-08-22T02:39:24.166-04:00"|"" |"" |"" |"" |"" |"" |"" |"" |"" |"Ryder, Elizabeth F."|"Whitefleet-Smith, JoAnn L."|"" |"" |"2019"|"" |"" |"" |"Bioinformatics & Computational Biology"|"Interdisciplinary"|"" |"This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review."|"" |"" |"" |"" |"Major Qualifying Project"|"Champlin, Daniel Mathieu"|"Payano, Jennifer A."|"O'Connell, Eoin J."|"" |"In A4 and other subclusters of mycobacteriophages, DNA primase is a two-domain protein made from two genes with significant overlap that are read in different open reading frames. These genes create a functioning protein through an unknown mechanism. Our investigations using multiple sequence alignments and protein modelling do not support intein splicing, ribosomal frameshifting, or RNA polymerase slippage as mechanisms of forming a functional\nDNA primase. Preliminary RT-PCR results suggest both domains are transcribed on one transcript."|"" |"" |"" |"" |"http://rightsstatements.org/vocab/InC/1.0/"|"" |"Worcester Polytechnic Institute"|"2019-04-23" |"" |"" |"E-project-042319-171703"|"" |"" |"" |"" |"W/"f0ff50b49d083b80eca99bfe90e9b67529584230""|"https://digital.wpi.edu/show/nc580q656"