Student Work
Molecular characterization of equine opioid receptors
PubblicoOpiates have been used for centuries to treat pain. The use of opiates on horses produces dysphoric side effects. The [mu]-receptor has been sequenced in five organisms. An equine cDNA library was created from horse brain. The use of rt-PCR to construct a probe of or clone directly the [mu]-receptor was ultimately unsuccessful. Once cloned, further experiments to elucidate the signal transduction pathway, distribution of receptor throughout the CNS, and binding kinetics may lead to more effective analgesics.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- 00D093M
- Advisor
- Year
- 2000
- Sponsor
- Date created
- 2000-01-01
- Resource type
- Major
- Rights statement
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Permanent link to this page: https://digital.wpi.edu/show/n870zt940