Student Work
Optimization and Validation of a Pathogenesis Survival Assay with the C. elegans Sterile Mutant Fer-1
PubblicoAn infertile C. elegans mutant fer-1 was identified as a suitable substitute for wild type in evaluating the pathogenesis of C. albicans using a survival assay. The response of fer-1 mutant worms infected with avirulent C. albicans mutants or treated with fluconazole is statistically indistinguishable from the wildtype counterpart. The lifespan of uninfected fer-1 worms is marginally yet reproducibly shorter than wildtype, but the lack of progeny in sterile mutants makes them an ideal choice for otherwise labor-intensive lifespan analyses.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- E-project-042212-192727
- Advisor
- Year
- 2012
- Date created
- 2012-04-22
- Resource type
- Major
- Rights statement
- Ultima modifica
- 2021-02-02
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Articoli
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Validation_of_a_pathogenesis_assay_with_sterile_C_elegans.pdf | Pubblico | Scaricare |
Permanent link to this page: https://digital.wpi.edu/show/n870zs17p