Student Work
The Effects of Phytoestrogens on Osteoblast Differentiation
PublicDownloadable Content
open in viewerMenopause occurs because of declining levels of estrogen and puts women at risk for osteoporosis. Promensil, an over-the-counter medication containing phytoestrogens, is marketed to alleviate menopausal symptoms. The goal of this project was to look at the effects of Promensil and phytoestrogens on bone deposition, using a preosteoblast cell line and alkaline phosphatase activity as a marker of mineralization. Over five days, increasing concentrations of Promensil increased alkaline phosphatase activity in preosteoblast cells. Yet, cells indicated decreased confluence and cell viability at increasing Promensil concentrations.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- E-project-042822-101720
- 65036
- Keyword
- Advisor
- Year
- 2022
- Date created
- 2022-04-28
- Resource type
- Major
- Rights statement
Relations
- In Collection:
Items
Items
Thumbnail | Title | Visibility | Embargo Release Date | Actions |
---|---|---|---|---|
Phytoestrogen #1 MQP D term Draft (1).pdf | Public | Download | ||
Phytoestrogen #1 MQP Lab Notebook.pdf | Public | Download |
Permanent link to this page: https://digital.wpi.edu/show/n583xz44r