Candida albicans and Pseudomonas aeruginosa are 2 of the most common healthcare related diseases today. Candida is ranked the 4th most common cause of 46,000 healthcare associated bloodstream infections (CDC, 2013). Pseudomonas causes 51,000 infections in the bloodstream and at surgical sites (CDC, 2013). Due to their ability to form infectious biofilms on biotic/abiotic surfaces, they are rapidly becoming drug resistant. With few new drugs manufactured each year these infections pose serious public health threats. Filastatin is a small molecule that exhibits inhibitory properties. Growth phases of C. albicans and P. aeruginosa when exposed to Filastatin were examined. Results indicated that Filastatin does disrupt the initial growth of both C. albicans and P. aeruginosa.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Kacoyannakis, Kayli J.

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-043015-152407

Advisor

• Camesano, Terri Anne
• Rao, Reeta Prusty

Year

• 2015

Date created

• 2015-04-30

Resource type

• Major Qualifying Project

Major

• Interdisciplinary

Rights statement

• In Copyright