Before procedures on organs between the head and abdomen are conducted, subjects are administered Neuromuscular Blocking Agents (NMBAs) to induce muscle paralysis. Accurate assessment of the depth of neuromuscular block is important to prevent complications caused by improper administration of NMBAs. The Train of Four Method (TOF) is used to complete this assessment; however, current objective measuring devices are limited. The goal of this project was to re-design and re-develop a pre-existing MQP device that utilizes mechanomyography, the gold standard technology for determining Train of Four values. This resulted in the development of the ‘TwitchCLIP’ that was tested alongside a competing device.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Sorenson, Jon
• Comeau, Derek J.
• Budri, Elliana
• Kring, Nicole A.

Subject

• Health
• Innovation
• Industry
• Project-Based Learning

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-050421-100110
• 21791

Keyword

• Mechanomyography
• Medical Device
• Monitoring Device
• Train of Four
• Anesthesia

Advisor

• Sabuncu, Ahmet Can

Year

• 2021

UN Sustainable Development Goals

• 3 - Good Health and Well-being
• 9 - Industry, Innovation and Infrastructure

Date created

• 2021-05-04

Resource type

• Major Qualifying Project

Major

• Mechanical Engineering

Rights statement

• In Copyright

Last modified

• 2021-08-29