UCL tears are a serious injury in throwing sports that can hinder athletes from maximizing their potential due to lengthy and invasive rehabilitation procedures. Current standard treatment methods are invasive and have a long recovery time. Our goal was to create a minimally invasive alternative to the current treatment method. In collaboration with Dr. David Magit and BioSurfaces, Inc., we developed a novel biodegradable electrospun scaffold into which we can inject PRP. The scaffold would then be placed on the UCL in a minimally invasive insertion procedure. We hypothesized this device would sustain local delivery or PRP at the injury site, decreasing UCL repair time. We evaluated the physical and cytotoxic properties of the pouch and its ability to release an orthobiologic over time

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Holm, Camden

Publisher

• Worcester Polytechnic Institute

Identifier

• 23126
• E-project-050621-150854

关键词

• Platelet Rich Plasma
• Tissue engineering
• Ulnar Collateral Ligament
• Orthobiologic
• Scaffold
• Electrospinning

Advisor

• Pins, George D

Year

• 2021

Sponsor

• BioSurfaces Inc.

Date created

• 2021-05-06

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Rights statement

• In Copyright

最新修改

• 2021-08-29