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Palladium Catalyzed Non-directed Aromatic C-H Aminations Public

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One-step, non-directed C-H aminations of arenes has the potential to facilitate the synthesis of compounds with aromatic C-N bonds, which are important bulk and fine chemicals for the synthesis of biologically active molecules. Currently, these types of products are synthesized through sequential functional group interconversions. Our goal is to develop one-step, non-directed C-H amination reactions of arenes that are enabled by palladium catalysts and electrophilic amination reagents. The effect of palladium source, ligand, amination reagent, solvent, temperature and additives on the yield of amination reactions are investigated in detail.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-043014-105624
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  • 2014
Date created
  • 2014-04-30
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