The goal of this project was to document and evaluate the new technology of mitochondrial replacement therapy (MRT) and assess its technical, ethical, and legal problems to determine if it should be approved in the U.S. - We reviewed the current literature and interviewed academic researchers, in vitro fertility experts, and bioethicists. Based on this data, we recommend the FDA approve MRT for a small group of patients and closely monitor the progress of their offspring before conducting MRT on a large scale. We recommend approval only for treating mitochondrial disease, and assigning parental rights to the two nuclear donors. Although useful, animal models and in vitro studies are imperfect, so we really just need to move forward with closely monitored human experiments.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Caron, Emily Anne
• Grondin, Benjamin Sandstrom
• Eckler, Daniel Joseph
• Hester, Maureen Martha
• Barbery, Daniela

Subject

• Health
• Well-Being
• Industry
• Innovation
• Security

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-082515-102705

Mot-clé

• Medical care

Advisor

• Adams, David S.

Year

• 2015

Date created

• 2015-08-25

Emplacement

• Worcester

Resource type

• Interactive Qualifying Project

Rights statement

• In Copyright

Dernière modification

• 2022-04-01