Student Work
Rational design of biomimetic basal lamina analogs for applications in tissue engineering
PúblicoThe goal of this project was to develop a scaffold with an extracellular matrix composition that enhances epidermal cell adhesion by mimicking the basal lamina in native human skin. A high-throughput method was developed which facilitates surface conjugation of basal lamina components (fibronectin, laminin, and collagen) to a collagen-glycosaminoglycan membrane and allows for multiple isolated experiments performed in parallel. The findings of these studies will aid in the design of the "off-the-shelf" skin substitutes with optimal surface composition for epidermal regeneration.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- 03D050M
- Advisor
- Year
- 2003
- Date created
- 2003-01-01
- Resource type
- Major
- Rights statement
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