Student Work
Analyzing the dysfunction of profilin1 in ALS
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open in viewerAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease which affects motor neurons in the brain and spinal cord. This project analyzed the ALS-associated protein, profilin 1 (PFN1). Multiple experiments were completed in order to analyze what occurs when profilin is not functioning correctly. Cloning, transfection, creating knockdown lines, and observing cells using fluorescent imaging where among the tools used to analyze wildtype PFN1 and ALS-mutant PFN1.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- E-project-042516-123240
- Advisor
- Year
- 2016
- Sponsor
- Date created
- 2016-04-25
- Resource type
- Major
- Rights statement
Relações
- Em Collection:
Itens
Itens
Miniatura | Título | Acesso | Embargo Release Date | Ações |
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Botelho_Victoria_FinalPaper.pdf | Público | Baixar |
Permanent link to this page: https://digital.wpi.edu/show/js956h21n