Student Work
Interaction Mechanism of Modified Collagen-Binding Antimicrobial Peptide LL37 with Model Lipid Bilayers
PubblicoContenuto scaricabile
open in viewerAntibiotic-resistant bacteria and chronic wound infections pose a serious threat to patient health and overall quality of life. The goal of this project was to determine the action mechanism of fCBD-LL37 against phosphatidylcholine lipid bilayer using a quartz crystal microbalance with dissipation. At increased concentrations, fCBD interacted to a greater extent with the lipid bilayer indicating that the tethered fCBD-LL37 shows greater peptide bondage to bilayer. This is the foundation of the development of bipolymer-tethered AMPs for wound healing applications.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- E-project-042717-111659
- Advisor
- Year
- 2017
- Date created
- 2017-04-27
- Resource type
- Major
- Rights statement
Relazioni
- In Collection:
Articoli
Elementi
Thumbnail | Titolo | Visibilità | Embargo Release Date | Azioni |
---|---|---|---|---|
MQP_final-Rachel_Smith_and_Yoon_Lee.pdf | Pubblico | Scaricare |
Permanent link to this page: https://digital.wpi.edu/show/js956h083