Establishing a Connection between Alzheimer's Disease and Cellular Energy Transduction Public
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The prevalence of Alzheimers Disease (AD) is rising worldwide. Characterized by accumulation of amyloid-beta plaques in the brain, AD results in loss of cognitive and motor functions, with a theorized link to metabolism and ATP production. This study used transgenic AD-model and metabolic mutant Caenorhabditis elegans to investigate punicalagin and coenzyme Q10 treatments through behavioral and ATP-quantifying assays. Both treatments were successful in rescuing chemosensation in AD and metabolic mutant strains, suggesting a metabolic deficiency that results in olfactory dysfunction.
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Permanent link to this page: https://digital.wpi.edu/show/jq085m44r