MAGNETICALLY SEEDED BIOREACTOR FOR THREE-DIMENSIONAL TISSUE CULTUREPublic
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Current tissue culture techniques lack the ability to position cells into 3-D shapes without an exogenous scaffold. The goal of the project was to design a bioreactor that positions cells in 3-D and supports tissue growth. Collagen-coated agarose beads seeded with rat aortic smooth muscle cells were introduced into the bioreactor and positioned on a magnetic rod, forming a tube. The device was run for five days without contamination and met the design objectives.
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