Current tissue culture techniques lack the ability to position cells into 3-D shapes without an exogenous scaffold. The goal of the project was to design a bioreactor that positions cells in 3-D and supports tissue growth. Collagen-coated agarose beads seeded with rat aortic smooth muscle cells were introduced into the bioreactor and positioned on a magnetic rod, forming a tube. The device was run for five days without contamination and met the design objectives.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Harel, Yuval Adam
• Chin, Alexander Wing
• Kutikov, Artem Boris

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042610-105002

Advisor

• Lambert, Christopher R.
• Page, Raymond L.
• Rolle, Marsha Whitney

Year

• 2010

Date created

• 2010-04-26

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Rights statement

• In Copyright

License

• All rights reserved

Last modified

• 2021-02-02