Mutations in mig-10 and unc-53 in C. elegans result in defects in axon guidance and excretory canal outgrowth. To better understand these genes' effects on migration and outgrowth, single and double mutant phenotypes were compared. In mig-10 mutants, excretory canal truncation is first observed during embryogenesis. Rescue experiments show that MIG-10 functions cell autonomously in the excretory cell. Phenotypes of single and double mutants suggest that mig-10 and unc-53 may have varying functions in different cells.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Hashmi, Sana K
• Kuhlwein, Mark Edward

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042711-150421

Advisor

• Ryder, Elizabeth F.

Year

• 2011

Date created

• 2011-04-27

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright