A stage-specific switch of surface composition in Caenorhabditis elegans has been identified which is inducible by growth conditions. Wild-type worms grown in the presence of a crude pheromone extract do not switch off the epitope for the M37 monoclonal antibody between the L1 and L2 developmental stages. To determine what genes and cells are required for this inducible larval display of surface antigens, antibody staining with M37 was performed on chemosensory mutants. Results indicate that ciliated neurons are required.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Olsen, Douglas Patrick

Publisher

• Worcester Polytechnic Institute

Identifier

• 99D080M

Advisor

• Politz, Samuel M.

Year

• 1999

Date created

• 1999-01-01

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright