The goal of this project was to study the binding and deactivation potential of the AMP cecropin P1 with eleven strains of E. coli with varying LPS membrane structures, using the quartz crystal microblance with dissipation (QCM-D. Three strains of E. coli (O157:H7, O113:H4, and O35:K-:H10) showed preferential binding with cecropin P1 and resulted in a higher percentage of the bacteria dead when in the presence of the AMP.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Thomas, Christine I.
• Kadilak, Andrea L.

Contributors

• Camesano, Terri Anne
• Strauss, Joshua
• Liu, Yatao
• Pinzon-Arango, Paola

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-033008-212524

Advisor

• Camesano, Terri Anne

Year

• 2008

Date created

• 2008-03-30

Resource type

• Major Qualifying Project

Major

• Chemical Engineering

Rights statement

• In Copyright

License

• All rights reserved

Last modified

• 2021-12-13