Utilizing the Quartz Crystal Microbalance with Dissipation to Bind Cecropin P1 to Escherichia coliPublic
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The goal of this project was to study the binding and deactivation potential of the AMP cecropin P1 with eleven strains of E. coli with varying LPS membrane structures, using the quartz crystal microblance with dissipation (QCM-D. Three strains of E. coli (O157:H7, O113:H4, and O35:K-:H10) showed preferential binding with cecropin P1 and resulted in a higher percentage of the bacteria dead when in the presence of the AMP.
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