Blood coagulation is an important aspect of hemostasis in the human body. Under normal circumstances, the blood coagulates using two different pathways, the intrinsic and the extrinsic. The extrinsic pathway works to counteract trauma but may lead to stroke forming clots. Components for an assay were created so that an assay could be designed to test the functionality of the proteins involved in the clotting cascade: Tissue Factor, factor VII, and factor X when used in conjunction with Template Directed Assembly (TDA) on a nickel-nitriloacetic acid (Ni-NTA) derived liposome.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Misch, Alexander

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042512-205109

Advisor

• Page, Raymond L.
• Camesano, Terri Anne

Year

• 2012

Sponsor

• Blue Sky Biotech

Date created

• 2012-04-25

Resource type

• Major Qualifying Project

Major

• Chemical Engineering
• Biomedical Engineering

Rights statement

• In Copyright

License

• All rights reserved