Student Work
Development of methods for synthesis of the huperzine alkaloids
PublicThe primary goal of this project is to explore the synthesis of huperzine alkaloids via the photoinitiated intramolecular ylide alkene cylcloaddition. Huperzine A and B are both potent inhibitors of acetylcholinesterase, the enzyme responsible for the degradation of acetylcholine. Thus improved synthetic approaches to huperzine A and B could prove useful in developing new therapies for diseases which are manifested by low acetylcholine levels.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- 00D205M
- Advisor
- Year
- 2000
- Date created
- 2000-01-01
- Resource type
- Major
- Rights statement
Relations
- In Collection:
Items
Permanent link to this page: https://digital.wpi.edu/show/cn69m721v