A major component contributing to the ability of nematodes to survive in a diversity of environments may be their ability to alter their surface antigen composition. In doing this, free-living nematodes may be able to avoid pathogenic microbial infections and parasitic nematodes may be able to avoid host’s immune response, both of which rely on recognizable antigens and epitopes located in glycoproteins on the surface of the worm. Two genes, srf-6 and nsy-1, have been shown to affect surface antigen presentation and prior evidence suggests that they are the same gene. This MQP aims to employ complementation tests to investigate whether srf-6 and nsy-1 mutations affect the same genetic function.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Hu, Alexander JianSheng

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042717-125615

Advisor

• Politz, Samuel M.
• Olsen, Carissa Lynn

Year

• 2017

Date created

• 2017-04-27

Resource type

• Major Qualifying Project

Major

• Biochemistry

Rights statement

• In Copyright