This MQP designed a method to morphometrically analyze magnetic resonance images of human lumbar intervertebral discs to determine a range of sizes of semi-customized Artificial Disc Replacements. The method was validated by comparing measurements of immature bovine spines taken from magnetic resonance images with measurements from physical specimens and published study data. The results indicated 86-98% accuracy of disc width and depth and 80% accuracy of disc height. Human data extraction revealed measurement accuracy of 85-99%, with the exception of posterior disc height. Ultimately, this methodology will assist in determining the range of sizes for semi-customized Artificial Disc Replacement.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Pitreau, Brian Robert
• Brown, Jessica K.
• Warner, Elaine Ellen

Publisher

• Worcester Polytechnic Institute

Identifier

• 02D332M

Advisor

• Pins, George D
• Sotak, Christopher H.

Year

• 2002

Date created

• 2002-01-01

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Rights statement

• In Copyright